• Donald Danforth Plant Science Center

    Your Only Statewide Network

    Your Only Statewide Network

  • Bond Life Sciences Center

    Your Voice For Missouri Life Sciences

  • Jordan Valley Innovation Center

    Business Savings Plans

  • Washington University in St. Louis - School of Medicine

    Your Only Statewide Network

  • MRIGlobal

    Your Voice For Missouri Life Sciences

  • Bayer Crop Science

    Business Savings Plans

Missouri Biotechnology Association is pleased to announce the appointment of our 2022-2023 board of directors.


Missouri Biotechnology Association (MOBIO) is the only statewide membership group that speaks with one voice to advance and champion the life sciences in Jefferson City, across the state, and in Washington, D.C. MOBIO represents most extensive and broadest cross-section of life science organizations including businesses, higher education, medical research, start-ups, agri-science and related firms involved in research, development, and commercialization of the life sciences. MOBIO serves to connect, develop, and advance the state’s bioscience community.

MOBIO members benefit from a strategic focus to support the enrichment and growth of the biosciences in Missouri through:

Statewide Network

MOBIO connections make a difference, specializing in meaningful business-to-business engagements and bridging: 

  • A network of diversified thought leaders
  • Business leaders with policymakers
  • Entrepreneurs with investors
  • Members to greater market potential 

Members connect at regional, national, and international levels with science, education, and commercial networks to advance business and enrich the industry. 

MOBIO is the catalyst, accelerating growth and leveraging high-value relationships for our vibrant life sciences community. 

Science & Policy

MOBIO advocates for Missouri’s life sciences and technology sectors.  Maintaining a sophisticated understanding of current dynamics, MOBIO serves as your trusted voice for bipartisan engagement and leadership within the Missouri State Capitol.

  • MOBIO forges meaningful relationships between public and private sector leaders to:
  • Defend companies large and small
  • Obtain and safeguard public investment
  • Secure state funding for Missouri's life science industry 

The strength of MOBIO's collective voice consistently delivers a compelling message to advance pro-science, pro-business legislative policy.    

Member Savings

MOBIO saves members real money, providing access to numerous partner organizations that offer significant discounts on relevant industry products and services.

  • R & D
  • Laboratory
  • Finance & Administration
  • Facilities & Operations
  • Communications & Data

All MOBIO members are entitled to preferred purchasing power. There is NO fee to participate.

MOBIO Member Highlight

Avadel Pharmaceuticals, with U.S. headquarters in St. Louis, MO: working to transform the lives of people with narcolepsy


Avadel is a biopharmaceutical company focused on transforming medicines to transform lives. Our approach includes applying innovative solutions to the development of medications that address the challenges patients face with current treatment options.

Our current lead drug candidate, LUMRYZ™ (sodium oxybate) for extended-release oral suspension was first conceived by an employee having a loved one with narcolepsy, a chronic neurological disorder in which the brain can’t regulate sleep-wake cycles. Based upon our heritage of drug delivery technology, the mission to bring an extended-release formulation of sodium oxybate to patients living with this disorder has been underway for approximately 10 years.

Sodium oxybate has been studied in the treatment of narcolepsy since the 1970s. Immediate-release sodium oxybate first received FDA approval in 2002 for the treatment of narcolepsy and is recognized by many as the standard of care treatment for this chronic condition. However, the only commercially available formulations require an unusual dosing regimen: patients take one dose at bedtime, typically falling asleep in 5-15 minutes, and then must wake up, 2.5 to 4 hours later, to take their second dose of medication. This dosing regimen is counterintuitive for people with a sleep disorder and creates additional challenges for patients already suffering from disrupted night time sleep.

Sodium oxybate is a difficult drug moiety to apply traditional extended-release technology to; however, the propriety drug delivery technology platform from Avadel enabled us to develop a much-needed solution to the twice-nightly dosing regimen.

In Avadel’s REST-ON clinical trial, once-at-bedtime LUMRYZ demonstrated statistically significant and clinically meaningful improvements across all co-primary endpoints, specifically improving the amount of time that patients could stay awake, an overall improvement as assessed by their clinicians, and a reduction in cataplexy, which is sudden muscle weakness that people with Narcolepsy Type 1 experience, typically in response to an emotion, such as laughter or surprise. Cataplexy may be as profound as full-body collapse, or may be more subtle, such as dropping items or slurred speech. 

In July 2022, LUMRYZ received FDA Tentative Approval for the treatment of cataplexy or excessive daytime sleepiness in adults with narcolepsy. FDA Tentative Approval means that a medication has demonstrated efficacy, safety, and manufacturing quality. However, due to a patent that is listed in the FDA’s Orange Book, a final approval decision cannot be given until after disposition of the patent. In this regard, the US District Court for the District of Delaware recently ruled that the patent blocking a final approval decision for LUMRYZ was improperly listed and ordered the patent removed from the FDA’s Orange Book. Upon removal of that patent from the Orange Book, Avadel will be able to request a transition from Tentative Approval to Final FDA Approval. 

Our delay in final FDA approval has not deterred us from our mission: we know patients are desperate for an option that will not require a forced, middle-of-the-night awakening, and they motivate us to ensure we urgently bring LUMRYZ to the narcolepsy community. 

Our Values are key to how we will fulfill this promise; at Avadel, it was imperative that these are not simply printed words, but that they imbue how we will serve patients – with LUMRYZ and beyond. 

Avadel Values 

In everything we do, we consider the patient experience, listening to their needs as we pursue the development and delivery of medicines that will have the most meaningful impact on those we serve.

We live the Avadel values so we can be the best for our patients, our community, and each other.

· Relentless

We are relentless in our pursuit of solutions to address the challenges patients face with current treatment options. We have the tenacity and burning desire to overcome obstacles and never give up. We act with a sense of urgency because we understand that patients shouldn’t wait for innovative solutions. We passionately believe in what we are doing and whom we are doing it for – the patient.

· Confidence with Humility

We are confident in our ability to recognize and overcome the challenges before us, yet we know when to ask for support. We are confident in our individual expertise, yet humble enough to know we don't have all the answers. We push each other to be our best and treat each other with respect. 

· Courageous

We recognize that it takes courage to make the bold decisions that can have the greatest impact for patients. We ask the tough questions because if not us, then who? Our diverse team sees our challenges as our biggest opportunities and continually pushes outside of their comfort zones to drive meaningful progress.

· Insights to Impact

We listen to our stakeholders, use data to drive decisions, and act on what we learn. We use insights to identify opportunities and take actions that deliver the greatest impact for patients. Our efforts are thoughtful and evidence-based, resulting from a deep understanding of what it takes to effect meaningful change for patients and those who care for them.

· Togetherness

We strive to create a level of connectivity that goes beyond working together. Rooted in the trust we earn every day, our team is inclusive, valuing diverse perspectives and work every day to lift each other up in pursuit of improving the lives of the patients we serve. This translates into one team driving success for each employee, success for the company, and most importantly, success for every patient.

We are proud of our values, of our unique offering based upon our propriety technology, and the substantial unmet need that once-at-bedtime LUMRYZ will fulfill, if final FDA approval is granted. Avadel is also proud to have our U.S. office in Missouri; as we expand, we look to harness talent in the biotechnology industry to be part of our mission to best serve patients.

MOBIO Breakthrough

Join us for MOBIO's Breakthrough of the Month series, where we explore Missouri's new and sometimes hidden biotech industry.  

This is a virtual learning platform for the greater life science community where we highlight and discuss novel discoveries, new business opportunities, and potential partnerships. 

This is a FREE presentation that is open to those in the life-science community. 

Are you interested in featuring your organization or discovery?  Please reach out to us, via email.

Tell Your Story

Please schedule your organization or recommend an area of interest.

Email Us


Miss a Breakthrough?  No problem, monthly recordings are archived for your convenience.



Invite a coworker or colleague to attend.